Cleopatra of Macedon (355/4-308 BCE), daughter of Philip II of Macedon (reign 359-336 BCE) and his Molossian queen, Olympias of Epirus (c. 375-316 BCE), was the only full sister of Alexander the Great (reign 336-323 BCE). Born in Pella, the capital of the ancient kingdom of Macedonia, Cleopatra grew up as a royal princess in the Argead court. She later became the queen of Epirus through her marriage to her maternal uncle, Alexander I of Epirus (reign 343/2-331 BCE). Their son, Neoptolemus II (reign 302 to 297 or 295 BCE), was very young when his father left for a military expedition in Italy. In his absence, Cleopatra reigned as a regent almost independently for a few years.
More about: Cleopatra of MacedonDefinition
Timeline
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c. 355 BCE - 308 BCELife of Cleopatra of Macedon, Alexander the Great's sister.
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336 BCECleopatra of Macedon marries Alexander I of Epirus.
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334 BCEAlexander I of Epirus leaves for campaign, Cleopatra of Macedon rules as regent in his absence.
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331 BCECleopatra of Macedon's husband, Alexander I of Epirus is killed at the Battle of Pandosia.
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323 BCEDeath of Alexander the Great, beginning of The Hellenistic Period / The Hellenistic World.
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322 BCECleopatra of Macedon moves from the Argead court in Pella to Sardis to marry Perdiccas.
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322 BCE - 275 BCEThe Wars of the Diadochi, also known as the Wars of Alexander's Successors.
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321 BCELysimachus marries Antipater's daughter Nicaea.
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319 BCEDeath of Antipater, regent of Macedon.
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316 BCEDeath of Olympias, mother of Alexander the Great.
