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1143 - 1180Reign of Byzantine emperor Manuel I Komnenos.
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1144 - 1146Byzantine emperor Manuel I Komnenos wins victories in Cilicia, Syria and Asia Minor.
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1149A fleet led by George of Antioch attacks Constantinople.
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1155 - 1157The Byzantines unsuccessfully invade southern Italy.
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1158Byzantine emperor Manuel I Komnenos signs a treaty with William I of Sicily.
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1161Byzantine emperor Manuel I Komnenos marries Maria of Antioch.
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1171Byzantine emperor Manuel I Komnenos arrests 10,000 Venetian traders across the empire to limit their stranglehold on trade.
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17 Sep 1176A Byzantine army is ambushed by the Seljuks at the battle of Myriokephalon in Phyrgia.
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24 Sep 1180Death of Byzantine emperor Manuel I Komnenos.