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c. 3600 BCEFirst appearance of silk in China.
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c. 2700 BCEThe earliest known examples of woven silk from Qianshanyang, China.
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130 BCEThe Silk Road is officially opened.
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129 BCEParthians conquer Mesopotamia. The Silk Road to China is now controlled by the Parthians.
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27 BCE - 14 CEReign of Augustus Caesar in Rome, Chinese silk is very popular.
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161 CE - 180 CEReign of Emperor Marcus Aurelius in Rome, Chinese silk popularity endures.
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527 CE - 565 CEReign of Emperor Julian of the Eastern Roman (Byzantine) Empire. Beginning of Byzantine silk industry.
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542 CEThe bubonic plague, thought to have been brought through the Silk Road, decimates Constantinople.