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c. 1570 BCE - c. 529 CEWorship of the goddess Isis in Egypt.
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c. 367 BCE - 529 CEWorship of the goddess Isis spreads outside Egypt's borders to Greece and Rome.
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47 BCECleopatra VII is sole ruler of Egypt; she presents herself as the goddess Isis.
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c. 42 CE - c. 62 CEThe evangelical missions of St. Paul; Isis worship dominates the Mediterranean.
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380 CEEmperor Theodosius I outlaws pagan practices including the worship of Isis.
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529 CEEmperor Justinian closes the Temple of Isis at Philae, Egypt, effectively ending worship of the goddess.