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30 Mar 1432Mehmed II is born.
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1437Mehmed II is appointed governor of Amasya.
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1444Mehmed II inherits the throne after Sultan Murad II abdicates.
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10 Nov 1444Murad II resumes defeats Crusader forces at the Battle of Varna.
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1451 - 1481Mehmed II rules as the Sultan.
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5 Feb 1451Mehmed II succeeds Murad as sultan following his death.
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31 Aug 1452Construction of fortress Rumelihisari is complete.
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6 Apr 1453Siege of Constantinople begins.
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29 May 1453Ottoman Sultan Mehmed II sacks Constantinople.
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1454 - 1459Ottoman campaigns in Serbia.
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1456Ottoman forces besiege Trebizond.
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22 Jul 1456Mehmed II is dealt his first major defeat at the Siege of Belgrade.
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1461Ottoman forces under Sultan Mehmed II capture Trebizond, ending the Empire of Trebizond.
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1461David Megas Komnenos, the last Emperor of Trebizond, is deposed by the Ottomans.
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17 Jun 1462Mehmed II defeats Vlad III in the Battle of Târgoviște.
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1463 - 1479The Ottomans fight a long war against the Venetians over their possessions in the Aegean.
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c. 1463 - 1470The Mosque of the Conqueror is constructed in Constantinople.
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1465Mehmed II oversees construction of Topkapi Palace, the new seat of his empire.
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3 May 1481Mehmed II falls ill during a military expedition and subsequently dies, leading to the succession of his eldest son Bayezid II to the throne.