The Battle of Issus, on 5 November 333 BCE, was Alexander the Great's second battle against the Persian army and the first direct engagement with King Darius III, near the village of Issus in southern modern-day Turkey. It was a major victory for Alexander, defeating the Achaemenid Empire and causing Darius III to flee the battlefield.
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5 Nov 333 BCEBattle of Issus. Alexander the Great is victorious against Darius III of Persia.
