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Jan 329 BCE - May 327 BCEAlexander conquers Bactria and Sogdiana.
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293 BCEAntiochos is appointed vice-king of the Upper-Satrapies by his father Seleucus I Nicator.
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c. 280 BCEIncursion of northern nomads (Sakas) on Seleucid territories.
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c. 209 BCESogdians make themselves independant, using the fact that Euthydemos I of Bactria was besieged in Bactra by Antiochos III.
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c. 200 BCESakas conquer the Sogdiana part of the Iaxartes.
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c. 200 BCE - c. 100 BCEScythians tribes migrate into Bactria, Sogdiana and Arachosia.