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c. 1425 - 1532The Inca Empire flourishes in South America.
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1438 - 1471Pachacuti Inca Yupanqui reigns as the leader of the Inca Empire.
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c. 1450Pachacuti Inca Yupanqui founds Machu Picchu in the High Andes.
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c. 1510The Inca abandon the settlement of Machu Picchu.
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1532Francsico Pizarro and the Spanish conquistadors arrive in South America.