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400 BCE - 100 CEThe Pukará civilization flourishes north of Lake Titicaca.
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200 CE - 1000 CETiwanaku Empire flourishes based around Lake Titicaca.
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1000 CE - 1100 CETiwanaku is abandoned, probably due to a series of severe droughts.
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c. 1425 CE - 1532 CEThe Inca Empire flourishes in South America.
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1471 CE - 1493 CEReign of Inca Tupac Yupanqui who doubles the size of the Inca Empire.