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293 BCEAntiochos is appointed vice-king of the Upper-Satrapies by his father Seleucus I Nicator.
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250 BCEFormer satrap Diodotos rebels against Seleucid king Antiochos I, creating the Greco-Bactrian kingdom.
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c. 171 BCEEucratides begins his uprising against Greco-Bactrian king Demetrios II.
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c. 145 BCEEucratidia is taken by the Sakas.
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c. 139 BCEEucratidia is looted to the ground by the Yuezhei.