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668 BCEMegara founds the colony of Byzantium.
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478 BCESpartan general Pausanias is given command of a force and takes both Cyprus and Byzantium.
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c. 475 BCEAthenian general Cimon defeats Spartan general Pausanias and takes Byzantium.
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340 BCEPhocion defeats Philip II of Macedon at Byzantium.
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527 CE - 565 CEReign of Byzantine Emperor Justinian I.
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Jan 532 CEThe Nika Revolt lasts over a week in Constantinople during the reign of Justinian I. The disturbance caused the destruction of much of the central city area and was quashed after a significant loss of life.