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262 BCE: Rome besieges and sacks Agrigento on Sicily in one of the first actions of the First Punic War.
212 BCE: A Carthaginian army is defeated in Sicily by a Roman army led by Marcellus. Syracuse falls to Rome who now control the island.
204 BCE - 203 BCE: Scipio Africanus wins two battles and besieges Utica in North Africa.
149 BCE: Rome sends an army of 80,000 infantry and 4,000 cavalry to attack Carthage.
148 BCE: The Roman siege of Carthage, in its second year, remains unsuccessful.
146 BCE: Scipio Africanus the Younger sacks Carthage and enslaves its population.
86 BCE: The Roman general Sulla sacks Athens and the port of Piraeus.
52 BCE: After becoming trapped and besieged at Alesia, Vercingetorix surrenders to Caesar.
51 BCE: Caesar's siege and capture of Uxellodunum ends the Gallic War.
49 BCE: Julius Caesar besieges Massilia.
43 CE: Maiden Castle, a Celtic hilltop fort in southern Britain, is captured by Roman legions.
70 CE: The city of Jerusalem is besieged and captured by Rome; the Second Temple destroyed.