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650 CE
660 CE
656 CE - 661 CE: The murder of Caliph Uthman causes the eruption of the First Fitna (civil war). Muawiya surfaces as a major opposer of the Rashidun Caliphate.
656 CE: The Battle of the Camel.
656 CE - 661 CE: Ali ibn Abi Talib succeeds Uthman to become the fourth and final caliph of the Rashidun Caliphate.
657 CE: Battle of Siffin.
657 CE: Ali ibn Abi Talib moves his empire's capital to Kufa in Iraq.
661 CE: Caliph Ali is assassinated by the Kharijites.