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1505 CE - 1961 CE: The Estado da India is in existence, that part of the Portuguese Empire from East Africa to Japan.
1505 CE: The Portuguese begin to attack cities and build forts along the Swahili Coast in order to control trade.
1510 CE - 1961 CE: Goa on the west coast of india is a Portuguese colony.
1510 CE: Afonso de Albuquerque conquers Goa in India for Portugal.
1511 CE: Afonso de Albuquerque captures Malacca in Malaysia for Portugal.
1511 CE - 1641 CE: Malacca in Malaysia is a Portuguese colony.
1515 CE: Hormuz at the mouth of the Persian Gulf is colonized by the Portuguese.
1518 CE: The Portuguese establish a fort at Colombo, Sri Lanka.
1519 CE - 1522 CE: Ferdinand Magellan's expedition circumnavigates the globe for the first time.
1519 CE: The Portuguese establish a fort at Kollam in India.
1521 CE: The Portuguese establish a fort at Chaul in India.
1530 CE: Portuguese Goa replaces Cochin as the capital of the Estado da India.
1533 CE: A papal bull establishes the archdiocese of the Estado da India.
1543 CE: Three Portuguese mariners accidentally land in Japan, the first Europeans to do so.
1546 CE: The Portuguese establish a formidable fortress on Mozambique Island.
1557 CE: The Chinese Ming Dynasty grants the Portuguese a trading base of their own at Macao.
1571 CE - 1639 CE: The Portuguese control the port of Nagasaki in Japan.
1571 CE: The Japanese daimyo Omura Sumitada grants the Portuguese control of Nagasaki.
1596 CE: The Dutch arrive in Southeast Asia and challenge the Portuguese and their empire.
1604 CE: A Council of State is established at Portuguese Goa.
1622 CE: The Persians, with English assistance, take control of Hormuz from the Portuguese.
1633 CE: The Portuguese conquer the southern African kingdom of Mutapa.
1637 CE - 1638 CE: The Shimabara Rebellion in Japan, which the shogunate blames on Christians, leading to an expulsion of all Europeans.
1638 CE - 1644 CE: Dutch forces attempt to blockade Portuguese Goa.
1640 CE - 1668 CE: Spain is at war with Portugal.
1641 CE: The Dutch attack and take over Portuguese Malacca.
1656 CE: The Dutch attack and take over Portuguese Colombo.
1663 CE: The Dutch attack and take over Portuguese Cochin.
1799 CE - 1815 CE: Portuguese Goa is occupied by the British during the Napoleonic Wars.
1961 CE: Portuguese Goa is invaded by the Indian military.
1999 CE: Portuguese Macao is handed over to China.