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280 BCE
270 BCE
260 BCE
250 BCE
240 BCE
230 BCE
220 BCE
210 BCE
200 BCE
190 BCE
275 BCE: Ptolemy II invades the Meroitic Nubian kingdom and annexes Lower Nubia.
205 BCE - 185 BCE: Upper Egypt and Lower Nubia secede from the Ptolemaic Kingdom with the support of Meroe. Two Egyptians, Horwennefer and his successor Ankhwennefer are declared as Pharaoh in the now independent territories.