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272 CE: Possible year of Emperor Constantine's birth.
308 CE: Constantine I named "caesar" of the west.
330 CE: Constantinople is founded on the site of old Byzantium as "the new Rome."
331 CE: The Great Palace of Constantinople is first built by Constantine I.
337 CE: Death of Constantine.
337 CE: Death of Emperor Constantine I.
360 CE: First Hagia Sophia built in Constantinople.
363 CE: Death of Julian the Apostate.
379 CE - 395 CE: Reign of Theodosius the Great.
391 CE: Christianity becomes official religion of Empire.
410 CE - 413 CE: The Theodosian Walls are built to better protect Constantinople.
527 CE: Coronation of Justinian I and Theodora in the Hagia Sophia Church in Constantinople.
532 CE: Nika Revolt in Constantinople.
532 CE: Hagia Sophia rebuilt by Justinian.
532 CE - 537 CE: Hagia Sophia is built anew in Constantinople.
626 CE: A coalition of Persians, Slavs, Avars and Bulgars unsuccessfully lays siege to Constantinople.
674 CE - 678 CE: The Arab Umayyad Caliphate unsuccessfully besieges Constantinople.
678 CE: First recorded use of Greek Fire in Byzantine warfare during the Arab siege of Constantinople.
705 CE: Justinian II besieges Constantinople and reinstates himself as Byzantine emperor, removing the usurper Tiberios III.
711 CE: Pope Constantine visits Constantinople at the invitation of Byzantine emperor Justinian II.
717 CE - 718 CE: Greek Fire is used by Byzantine ships to attack an Arab fleet besieging Constantinople.
730 CE: Byzantine emperor Leo III decrees that all religious icons be destroyed.
741 CE - 775 CE: Reign of Byzantine emperor Constantine V
821 CE - 822 CE: Greek Fire is used by Byzantine ships to attack a Slav fleet besieging Constantinople.
821 CE - 823 CE: Thomas the Slav unsuccessfully besieges Constantinople.
867 CE - 886 CE: Reign of Byzantine emperor Basil I.
907 CE: Oleg, Prince of Kiev, attacks the Byzantine capital Constantinople.
941 CE: Greek Fire is used by Romanos I's fleet against a Russian fleet attacking Constantinople.
976 CE - 1025 CE: Reign of Byzantine emperor Basil II.
994 CE: Trdat the Architect completes his reconstruction of the dome of Hagia Sophia, Constantinople.
1025 CE - 1028 CE: Reign of Byzantine emperor Constantine VIII.
1097 CE: The First Crusaders arrive at Constantinople.
1133 CE: Byzantine emperor John II Komnenos celebrates a triumph in Constantinople after five successful campaigns in Asia Minor.
1147 CE: The armies of the Second Crusade arrive in Constantinople.
1149 CE: A fleet led by George of Antioch attacks Constantinople.
1202 CE - 1204 CE: The Fourth Crusade is formed to recapture Jerusalem for Christendom. Instead, the Crusaders attack Constantinople.
1203 CE: The army of the Fourth Crusade arrives at Constantinople.
1204 CE: Constantinople is sacked by the Fourth Crusaders.
1204 CE: Count Baldwin of Flanders is made the first Latin Emperor of Constantinople.
1453 CE: Ottoman Sultan Mehmed II sacks Constantinople.