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1340 CE
1350 CE
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1345 CE - 1521 CE: The Aztec civilization flourishes in Mesoamerica.
1418 CE: Texcoco is temporarily conquered by Mexica and Tepanec forces.
1428 CE: The Triple Alliance is formed between Tenochtitlan, Texcoco and Tlacopan.
1450 CE: The Aztecs establish a garrison at Mitla in the Oaxaca Valley.
1485 CE: The Stone of Tizoc is carved depicting the Aztec king Tizoc attacking warriors from the Matlatzinca.
1487 CE: The Templo Mayor is completed at Tenochtitlan and inaugurated with the sacrifice of 20,000 captives.
1494 CE: Aztec leader Ahuitzotl conquers the central valleys of Oaxaca.
1499 CE: Aztec leader Ahuitzotl conquers the Soconusco region.
1507 CE: The Throne of Motecuhzoma II is carved. Also known as the Monument of Sacred War.
1521 CE: Texcoco provides ships and men to aide the Spanish siege of Tenochtitlan.
1521 CE: The Aztec capital of Tenochtitlan falls into the hands of Spanish forces led by Hernán Cortés.