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430 BCE
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150 BCE
426 BCE: The Athenian general Demosthenes launches an attack on the Aetolian hillmen.
366 BCE: An Athenian decree refers to the koinon (league) of the Aetolians.
344 BCE: Philip II of Macedon reorganizes the government of Thessaly.
338 BCE: Philip II of Macedon deliveres the city of Naupactus to the Aetolians.
330 BCE: According to Plutarch, the Aetolians capture the Akarnanian city of Oiniadai.
321 BCE: Antipater invades Aetolia.
301 BCE: Aetolia allies with Boeotia.
290 BCE - 270 BCE: The Aetolian League expands to bigger part of the shore of the Corinthian Gulf, Herakleia in Trachis, Lokris and in the Malian Gulf on the coasts of Phthiotis.
289 BCE: In northern Aetolia, joined Epirotian and Aetolian forces repel the Macedonian invaders.
280 BCE - 279 BCE: A coalition between the Aetolians and the Boeotians repel the Celtic invasion.
224 BCE: An Aetolian colony is established in the city of Same in the island of Cephallonia.
220 BCE - 217 BCE: A war is declared between the Symmachy and the Aetolian League, Sparta and Elis.
217 BCE: Philip V captures the Aetolian base of Phthiotic Thebes and installs a colony naming it after him, Philippi.
214 BCE - 205 BCE: First Macedonian War: Rome defeats Philip V of Macedon.
200 BCE - 196 BCE: Second Macedonian War: Roman victory.
197 BCE: Romans are victorious over Philip V of Macedon at Cynoscephalae.
192 BCE - 188 BCE: The Roman-Seleucid War.
172 BCE - 168 BCE: Third Macedonian War: Perseus of Macedon challenges Rome and is defeated.
150 BCE - 148 BCE: As a result of the Fourth Macedonian War, Aetolia is incorporated into the Roman Republic.